Compare and contrast the various types of autonomic receptors
What will be an ideal response?
There are two major types of autonomic receptors: (1) cholinergic receptors, to which acetylcholine (ACh) binds, and (2) adrenergic receptors, to which norepinephrine (NE) and/or epinephrine (E) bind. Cholinergic receptors include two subtypes: nicotinic, which are found on all postganglionic neurons, and muscarinic, which are found on effectors stimulated by the parasympathetic division and a few effectors stimulated by the sympathetic division. Adrenergic receptors include two major subtypes: alpha and beta. Alpha-1 receptors are found on most sympathetic targets and bind NE more readily than E, and the effect is always excitatory. Alpha-2 receptors are found on digestive system organs and binds more readily to NE than to E; the effect of binding is inhibitory. Beta-1 receptors are found on the heart's cardiac muscle and bind equally to NE and E; the effect is excitatory. Beta-2 receptors are found on smooth muscle in bronchioles and certain blood vessels; the effect is inhibitory.
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