The nurse would expect to see an order for a drug that blocks H2 receptors in a client with:
Standard Text: Select all that apply.
1. excess gastric acid production.
2. peptic ulcer disease.
3. gastroesophageal reflux disease.
4. allergic rhinitis.
5. seasonal allergies.
Correct Answer: 1,2,3
Rationale 1: Excess gastric acid production can be reduced by blocking H2 receptors.
Rationale 2: Symptoms of peptic ulcer disease are decreased when H2 receptors are blocked.
Rationale 3: When H2 receptors are blocked, gastric acid secretion is reduced, decreasing the symptoms of GERD.
Rationale 4: The symptoms of allergic rhinitis are the result of the activation of H1 receptors.
Rationale 5: The symptoms of seasonal allergies are the result of the activation of H1 receptors.
Global Rationale: Drugs that block H2 receptors such as ranitidine (Zantac) reduce gastric acid secretion and are used to treat peptic ulcer disease and gastroesophageal reflux disease. This histamine receptor activity is not related to allergic responses.
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