A cell has channels for Na+, K+, and Cl- in its plasma membrane. The resting membrane potential is –60 mV (cell interior negative). The intracellular and extracellular concentrations for these ions are given below, as is the calculated Nernst potential

A drug is applied to the cell that increases the permeability of the cell to Cl- (i.e., it opens Cl- channels). What effect will this drug have on the net movement of Cl- across the plasma membrane?

A. Net Cl- movement out of the cell will be increased.
B. Net Cl- movement into the cell will be increased.
C. There will be no change in the net movement of Cl-.


ANS: C

Anatomy & Physiology

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