The reticulocyte response in patients with moderate anemia is often misinterpreted as adequate if:
a. The count is not expressed in absolute terms or corrected for anemia.
b. The red cell indices are not considered.
c. A bone marrow aspirate is not examined.
d. Red cell morphology is not considered.
ANS: A
If only the percentage of reticulocytes is considered, a patient may appear to be making an adequate response to anemia. However, when the red count is considered, and either the absolute reticulocyte count or the reticulocyte production index is calculated, a truer picture can be obtained regarding adequacy of bone marrow response.
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