The nurse caring for older patients in an acute care facility is aware of the changes in drug metabolism that can occur in older adults. Which statement explains the most important factor that affects pharmacokinetics in older patients?
A) Changes in gastrointestinal (GI) motility increase the absorption time for many drugs.
B) Drug distribution is unpredictable due to metabolic and body-composition factors.
C) Preexisting chronic conditions complicate the distribution and metabolism of drugs.
D) Decreased renal and liver function contributes to an increased half-life for many drugs.
D
Feedback:
Changes in renal and liver function contribute significantly to the changes in pharmacokinetics that are common in older adults. While changes in GI motility, drug distribution, and preexisting conditions may be true for many patients, these factors are inconsistent.
You might also like to view...
29.6 à— 5.4 = _____
a. 15.984 b. 1598.4 c. l60 d. 159.84
The nurse researcher's study design includes an experimental group and a control group. After the study begins, the researcher finds that 60% of the experimental group and 75% of the control group have dropped out of the study
Because of the internal threat of mortality, the researcher abandons the study. In future studies what could the researcher do to help prevent this problem? 1. Have the participants sign a pledge to continue in the project prior to inclusion in the study group. 2. Call each of the participants who dropped out and insist that each honors his or her commitment to the study. 3. Allow a longer time for the study. 4. Try to establish a relationship with the participants.
Feeding tubes should be placed into the small intestine rather than the stomach if
a. the patient is comatose. b. a regular polymeric formula is being used. c. the patient prefers not to have a tube passing through his or her nose. d. the patient is expected to resume oral feedings within 1 to 2 weeks.
The Department of Homeland Security was created in 2002. The mission of this agency is
1. Prevent and deter terrorist attacks and protect against and respond to threats and hazards to the nation 2. Regulate nursing licensure 3. Ensure the safety of food and cosmetics 4. Regulate managed care organizations