The nurse is reviewing laboratory results for a client with a low level of intrinsic factor. Which blood smear report would help confirm the medical diagnosis of pernicious anemia?
1. Macrocytic and hypochromic red blood cells
2. Macrocytic and normochromic red blood cells
3. Microcytic and hypochromic red blood cells
4. Normocytic and normochromic red blood cells
Correct Answer: 2
Rationale 1: In pernicious anemia, the red blood cells are not hypochromic.
Rationale 2: In pernicious anemia, the red blood cells are too few in number, too large (macrocytic), and abnormally shaped, but they have a normal color because they contain a normal amount of hemoglobin.
Rationale 3: In pernicious anemia, the red blood cells are not microcytic or hypochromic.
Rationale 4: In pernicious anemia, the red blood cells are not of normal size. They are of normal color because they contain the normal amount of hemoglobin.
Global Rationale: In pernicious anemia, the red blood cells are too few in number, too large (macrocytic), and abnormally shaped, but they have a normal color because they contain a normal amount of hemoglobin.
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