Use your knowledge of amino acid characteristics to order the peptides below according to the net charge contributed by their side chains at physiological pH (~pH 7). Each peptide contains eight amino acids

Use the single-letter amino acid designations to generate your list, placing the most negatively charged peptide on the left and the most positively charged peptide on the right. In addition, for each peptide, list the total number of positive and negative charges. Remember that, at neutral pH, the amino terminus carries a positive charge and the carboxyl terminus carries a negative charge.
A. YGAKKRA
B. ARRKSTRK
C. DERKQNST
D. DDAEIYSA
E. NQSTYEEG


(D) This peptide has 4 negative charges and one positive charge. The peptide in (E) has 3 negative charges and one positive charge. The peptide in (C) has 3 negative charges and 3 positive charges. The peptide in (A) has 4 positive charges and one negative charge. The peptide in (B) has 6 positive charges and one negative charge.

Biology & Microbiology

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