Pain transduction begins when which event occurs?
1. Pain travels on the nociceptor to the spinal cord.
2. The pain impulse reaches the spinal cord to pass messages to neurons.
3. Local tissue injury causes release of chemical mediators of inflammation.
4. The pain impulse reaches the brain, to respond with a variety of actions.
Correct Answer: 3
Rationale 1: Pain traveling along the nociceptors occurs during pain transmission.
Rationale 2: The pain impulse reaches the spinal cord as part of pain transmission.
Rationale 3: When local tissue injury occurs, pain transduction begins in the nociceptor nerve endings.
Rationale 4: The pain impulse reaches the brain as a part of pain transmission.
Global Rationale: When local tissue injury occurs, pain transduction begins in the nociceptor nerve endings. Pain traveling along the nociceptors, pain reaching the spinal cord, and the pain impulse reaching the brain all occur during pain transmission.
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