Pharmacotherapy for Parkinson's disease is intended to
1. increase the amount of dopamine and reduce the amount of acetylcholine.
2. increase the amount of dopamine and acetylcholine.
3. reduce the amount of dopamine and increase the amount of acetylcholine.
4. reduce the amount of dopamine and acetylcholine.
1
Rationale 1: Parkinson's disease results in the death of neurons that produce dopamine. The balance is restored by increasing the levels of dopamine or by inhibiting the excitatory actions of acetylcholine.
Rationale 2: Parkinson's disease results in the death of neurons that produce dopamine. Due to the imbalance, dopamine is provided (levodopa), and anticholinergics can be administered as well. Acetylcholine is not increased.
Rationale 3: Dopamine is not reduced.
Rationale 4: Dopamine is not reduced.
Global Rationale: Parkinson's disease results in the death of neurons that produce dopamine. The balance is restored by increasing the levels of dopamine or by inhibiting the excitatory actions of acetylcholine.
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