What experimental evidence suggests that the N-terminal tails of histones participate in the formation of higher-order chromatin structure?

a) The tails cause histones to denature.
b) Chromatin fibers prepared with H4 histones lacking their tails cannot fold into higher-order fibers.
c) Chromatin fibers prepared with H4 histones possessing longer tails cannot fold into higher-order fibers.
d) The tails when acetylated cause the dissolution of the 30-nm fibers.
e) Chromatin fibers lacking tails are shorter.


Ans: c) Chromatin fibers prepared with H4 histones possessing longer tails cannot fold into higher-order fibers.

Biology & Microbiology

You might also like to view...

During which stage of development are germ cell layers first formed?

A. fertilization B. cleavage C. neurulation D. gastrulation E. organogenesis

Biology & Microbiology

The brain center for homeostatic control of the internal environment is the ________

a. hypothalamus b. cerebellum c. pons d. thalamus

Biology & Microbiology

Natural selection acts on ________, and ________ evolve.

A. individuals; populations B. populations; individuals C. individuals; individuals D. populations; populations

Biology & Microbiology

An amphipathic molecule has:a

two polar ends. b. two hydrophobic ends. c. a hydrophobic and a hydrophilic portion. d. only one hydrophobic end. e. only one hydrophilic end

Biology & Microbiology