Three major types of RNAs are mRNA, rRNA, and tRNA. For each of the conditions below, predict the consequences in terms of the population of proteins being synthesized in a particular cell and the effects on individual proteins

(a) An acridine dye—induced mutation (adds or deletes single bases in DNA) leads to an mRNA for one protein-producing gene. The condition is heterozygous in the involved cell.
(b) A deletion (homozygous) that removes approximately half of the rRNA genes.

What will be an ideal response?


(a) Population of proteins: Half of the protein products of that gene will be defective, and the other half will be normal. Individual protein: The protein should show multiple amino acid substitutions "downstream" from the point of the mutation. If a nonsense triplet is introduced, the protein will be shortened in the substituted region. (b) Population of proteins: There would be an overall reduction in protein synthesis. Individual proteins: All of the proteins would be made in their normal form but at reduced levels.

Biology & Microbiology

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