A 45-year-old man has a history of heart failure and is diagnosed with pulmonary arterial hyper-tension. Initially, he is prescribed treprostinil (Tyvaso) 3 breathes (18 mcg) per treatment session via the Tyvaso Inhalation System

Upon first administration, the patient feels nauseated, throat irritation, muscle pain, and experi-ences flushing. What is the best next course of action?
a. Continue medication administration with the addition of pain relievers.
b. Stop medication administration and con-tinue to the next treatment session.
c. Reduce dose to 1 to 2 breaths per session and then gradually increase to 3.
d. Change medication administration.


ANS: C
The initial dose for Tyvaso is 3 breathes (18 mcg) per treatment session. If not tolerated, the dose may be reduced to 1 to 2 breathes per session and then increased to 3. Tyvaso should be in-creased by 3 breathes every 1 to 2 weeks until 9 breathes (54 mcg) per treatment session is reached.

Health Professions

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