The nurse is developing a plan of care for a child who is receiving cyclophosphamide. What advice would the nurse expect to include?
A) Withholding food and fluids from the child during the infusion
B) Encouraging frequent voiding during and after the infusion
C) Monitoring for signs of anaphylaxis during infusion
D) Assessing the child for complaints of bone pain
Ans: B
Cyclophosphamide may cause hemorrhagic cystitis. Therefore, the nurse needs to provide adequate hydration and have the child void frequently during and after the infusion to decrease the risk of hemorrhagic cystitis. Fluids need to be encouraged, not withheld. Monitoring for anaphylaxis would be appropriate when asparaginase or etoposide is given. Bone pain is associated with the administration of filgrastim or sargramostim.
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