Type 2 heparin-induced thrombocytopenia is characterized by
a. formation of thrombi, causing vessel occlusion.
b. spontaneous epistaxis.
c. elevated prothrombin times.
d. massive peripheral ecchymoses.
A
Patients with immune-mediated heparin-induced thrombocytopenia (HIT) are at greater risk for thrombosis than bleeding. Vessel occlusion can result in the need for limb amputation, stroke, acute myocardial infarction, and even death. The resultant formation of fibrin platelet–rich thrombi is the primary characteristic of HIT that distinguishes it from other forms of thrombocytopenia and gives rise to its more descriptive name: white clot syndrome.
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