A patient has seasonal allergies and needs an antihistamine to control symptoms. The patient likes to have wine with dinner several times a week and wants to know which antihistamine will be the safest to take
The nurse will tell the patient to discuss which medication with the provider?
a. Cetirizine (Zyrtec)
b. Fexofenadine (Allegra)
c. Levocetirizine (Xyzal)
d. Loratadine (Claritin)
ANS: B
Fexofenadine is the least sedating of the second-generation antihistamines and so is the least likely to have synergistic effects with alcohol. Cetirizine, levocetirizine, and loratadine all have sedative side effects to some extent and thus would be less safe.
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