A nurse is teaching nursing students about the use of alpha-adrenergic antagonists. Which statement by the student indicates the need for further teaching?
a. "Alpha-adrenergic antagonists block alpha1 receptors on arterioles and veins."
b. "Dilation of arterioles has a direct effect on arterial pressure."
c. "Dilation of veins by alpha-adrenergic antagonists improves cardiac output."
d. "Venous dilation by alpha-adrenergic antagonists indirectly lowers arterial pressure."
ANS: C
Cardiac output is decreased as a result of the venous dilation caused by alpha-adrenergic antagonists. Alpha-adrenergic antagonists block alpha1 receptors on both arterioles and veins. When alpha1 receptors on arterioles are blocked by alpha-adrenergic antagonists, a direct effect on arterial pressure occurs. When alpha1 receptors on veins are blocked by alpha-adrenergic antagonists, an indirect effect on arterial pressure occurs.
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