A woman approaching menopause is interested in oral hormone replacement therapy to manage the symptoms. Which of the following statements should be included in her teaching plans?
1. Estrogen is cardio-protective for women.
2. Hormone replacement therapy is associated with a reduced incidence of breast cancer and pulmonary embolism.
3. Hormone replacement therapy is linked to higher rates of deep vein thrombosis and colorectal cancer.
4. Hormone replacement therapy is useful for women who are at an increased risk for the development of osteoporosis.
4. Hormone replacement therapy is useful for women who are at an increased risk for the development of osteoporosis.
Rationale:
Osteoporosis is associated to the reduction of estrogen. Hormone replacement therapy is encouraged for those women who are at an increased risk for the development of this disease. Estrogen was once thought to be cardio-protective for women, but newer studies refute these claims. There is an increased risk for breast cancer and pulmonary embolism for those women who are taking hormone replacement therapy. While the rates of deep vein thrombosis are increased, the rates of colorectal cancer are reduced in those taking hormone replacement therapy.
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