Which statement is true regarding biological response modifiers?

Question

1. They are used to treat transplant rejections.
2. Some are immunostimulants and, when given with other antineoplastic agents, help limit severe myelosuppression.
3. They alter the body's defense system to decrease the removal of foreign cancer cells.
4. They are less toxic than are most classes of antineoplastics.

Answer 1

Correct Answer: 2
Rationale 1: They are used to prevent transplant rejection, not to treat them.
Rationale 2: This is true regarding biological response modifiers.
Rationale 3: They alter the body's defense system by enhancing the removal of foreign cancer cells.
Rationale 4: Biological response modifiers are not less toxic than are most classes of antineoplastics.
Global Rationale: Hematopoietic growth factors promote the formation of specific blood cells. These drugs enhance the ability of the immune system to respond and reduce some of the myelosuppression caused by antineoplastic medications. BRMs are used to prevent transplant rejection, not to treat it. They alter the body's defense system by enhancing removal of foreign cancer cells. They are not necessarily less toxic.