Which of the following tissues is capable of causing the greatest biotransformation of drugs that cross the placenta and affect the fetus?
a. Liver of the fetus
b. Maternal organs
c. Placenta
d. Umbilical cord
ANS: B
Fetal biotransformation of drugs is believed to be minimal. The fetus relies on maternal plasma levels of a drug to clear the drug from the fetal circulation.
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