When the newborn female is born with ambiguous genitalia, the follow-up investigation discovers adrenogenital syndrome (also called congenital adrenal hyperplasia). The parents question why the baby's genitalia looks more male than female
The nurse would explain that: 1. The disorder caused the infant to be a hermaphrodite with both male and female sex organs.
2. The changes in the genitalia are due to increased androgens secondary to deficient cortisol.
3. The excessive cortisol caused the enlargement of the female tissue, creating a male appearance.
4. The child has only one sex chromosome resulting in an XO configuration.
2
Rationale 1: This statement is incorrect. The child's internal organs will be ovaries only.
Rationale 2: Deficient cortisol causes the amount of ACTH to be high, over stimulating the adrenal production of androgens which causes the pseudo-masculinization.
Rationale 3: The cortisol level is decreased, not increased.
Rationale 4: XO sex chromosomes describe Turner's syndrome, not CAH.
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