The client receives methotrexate (Rheumatrex). The nurse assesses for side effects of this drug. Which side effects are a primary concern for the nurse?
1. Hyperglycemia and fatigue
2. Nausea and vomiting
3. Hypertension and seizures
4. Ulcerative stomatitis and diarrhea
Correct Answer: 4
Rationale 1: Hyperglycemia is not an adverse effect of methotrexate.
Rationale 2: Nausea and vomiting are expected adverse effects and are not of primary concern.
Rationale 3: Hypertension and seizures are not adverse effects of this drug.
Rationale 4: Ulcerative stomatitis and diarrhea require suspension of therapy because they may lead to hemorrhagic enteritis and death from intestinal perforation.
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