Why does prothrombin G20210A increase the risk of thrombosis?
a. Makes prothrombin activation easier
b. Elevates prothrombin levels
c. Decreases binding of thrombin by antithrombin
d. Decreases binding of plasminogen to prothrombin
ANS: B
The prothrombin G20210A mutation results in elevated levels of prothrombin; this increases the risk of thrombosis, although the reason why is not clear.
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