A nurse is reviewing medications prior to administration to infant patients. An infant has been receiving a drug for 8 days that undergoes significant renal excretion. For what should the nurse monitor the infant?
a. Allergy to the medication
b. Signs and symptoms of toxicity specific to the medication
c. Vomiting, diarrhea, and gastrointestinal upset
d. Shrill cry and irritable behavior
ANS: B
Renal drug excretion is significantly reduced at birth, therefore the infant's ability to eliminate the medication is diminished. This allows the drug to stay in the system longer, increasing the risk of toxicity.
There is no indication that the patient is allergic to the medication if the infant has been taking it for 8 days already.
There is no indication that the patient should experience vomiting, diarrhea, or gastrointestinal upset because of significant renal excretion of a medication.
There is no indication that the patient should experience a shrill cry and irritable behavior because of significant renal excretion of a medication.
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