By binding to the Ca2+ channel proteins, drugs known as calcium channel blockers have two main effects. Name them. Why are some cells unaffected by these drugs?

What will be an ideal response?


Binding to calcium channels makes them less likely to open, effectively blocking the normal inward calcium current that would result from neural or endocrine stimulation. This causes vasodilation and a decrease in heart rate. Insensitive tissues have a different subtype of calcium channel.

Anatomy & Physiology

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