A nurse is caring for a client with schizophrenia. The client asks the nurse what causes the disease. Which response indicating the pathophysiology and etiology of the disease is appropriate by the nurse?
A) "Reduced blood flow to the thalamus interferes with the brain's filter, turning the normal flow of sensory information into an overload."
B) "There is an increased number of nicotinic receptors in the hippocampus, which makes it harder to form new memories and interpret sensory stimuli.
C) "Genetics do not seem to factor into the cause of the disease."
D) "The ventricles and sulci of the brain are decreased in size."
Answer: A
There are many abnormalities of the central nervous system in a client with schizophrenia. Reduced blood flow to the thalamus interferes with the brain's filter, turning the normal flow of sensory information into an overload. A decreased number of nicotinic receptors in the hippocampus makes it harder for the client with schizophrenia to form new memories and interpret sensory stimuli. Genetics seem to factor into the cause of the disease, as familial patterns of the disease are noted. In the client with schizophrenia, the ventricle and sulci of the brain are increased in size.
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