A patient with liver impairment needs an antiepileptic drug. What drug would be safest for patients with liver impairment?

A) Levetiracetam (Keppra)
B) Lamotrigine (Lamictal)
C) Phenobarbital
D) Valproic acid (Depakene)


A
Feedback:
Levetiracetam is a newer drug chemically unrelated to other antiepileptic drug. Most of the drug is excreted by the kidneys and is not metabolized by the liver so it would be safer for the patient with liver disease. The other options are all metabolized by the liver, so the patient with liver disease will need a lower dosage.

Nursing

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