A nurse is administering dalfopristin/quinupristin (Synercid) to a hospitalized patient. What are the most likely indications for these drugs? (Select all that apply.)
a. Urinary tract infection (UTI) with E. coli
b. Vancomycin-resistant E. faecium
c. Pneumococcal infection in a patient with hepatic failure
d. Peptic ulcer disease (PUD)
e. Methicillin-resistant S. aureus or S. epidermidis
B, E
The indications for treatment with dalfopristin/quinupristin are vancomycin-resistant E. faecium and methicillin-resistant S. aureus or S. epidermidis.
UTI and PUD are not indications for treatment with dalfopristin/quinupristin.
A patient with hepatic failure should not receive this medication because it has hepatotoxic ef-fects.
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