A pregnant mother (16 weeks' gestation) forgot and emptied her cat's litter box without gloves. She is extremely anxious and wants tested right away. Which test would the nurse prepare her for that would give rapid cytogenic analysis?

A) Ultrasonography
B) Fetal biopsy
C) Chorionic villus sampling
D) Percutaneous umbilical cord blood sampling


Ans: D
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Percutaneous umbilical cord blood sampling involves the transcutaneous insertion of a needle through the uterine wall and into the umbilical artery. It is used for prenatal diagnosis of hemoglobinopathies, coagulation disorders, metabolic and cytogenetic disorders, and immunodeficiencies. Fetal infections such as rubella and toxoplasmosis can be detected through measurement of immunoglobulin M antibodies or direct blood cultures. Results from cytogenetic studies usually are available within 48 to 72 hours. Fetal biopsy is used to detect certain genetic skin defects that cannot be diagnosed with DNA analysis. The tissue that is obtained following sampling of the chorionic villi can be used for fetal chromosome studies, DNA analysis, and biochemical studies. Ultrasonography makes possible the in utero diagnosis of hydrocephalus, spina bifida, facial defects, congenital heart defects, congenital diaphragmatic hernias, disorders of the gastrointestinal tract, and skeletal anomalies. Cardiovascular abnormalities are the most commonly missed malformation.

Health & Biomechanics

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