A nurse is teaching a female client with rheumatoid arthritis (RA) about taking methotrexate (MTX) (Rheumatrex) for disease control. What information does the nurse include? (Select all that apply.)

a. "Avoid acetaminophen in over-the-counter medications."
b. "It may take several weeks to become effective on pain."
c. "Pregnancy and breast-feeding are not affected by MTX."
d. "Stay away from large crowds and people who are ill."
e. "You may find that folic acid, a B vitamin, reduces side effects."


ANS: A, B, D, E
MTX is a disease-modifying antirheumatic drug and is used as a first-line drug for RA. MTX can cause liver toxicity, so the client should be advised to avoid medications that contain acetaminophen. It may take 4 to 6 weeks for effectiveness. MTX can cause immunosuppression, so avoiding sick people and crowds is important. Folic acid helps reduce side effects for some people. Pregnancy and breast-feeding are contraindicated while on this drug.

Nursing

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