The nasal salt glands of insectivorous lizards respond to injections of chloride ions by increasing secretions of sodium or potassium chloride, whereas injections of sodium or potassium ions do not increase the activity of the nasal salt glands
What difference in the routes of excretion of sodium and potassium ions compared to chloride ions accounts for the different responses of the lizards?
Excess sodium and potassium can precipitate as salts of uric acid and are excreted via the cloaca, whereas excess chloride ions can be excreted only via the salt gland. (L. C. Hazard et al. 2010 . Secretion by the nasal salt glands of two insectivorous lizard species is initiated by an ecologically relevant dietary ion, chloride. Journal of Experimental Zoology (Ecol Genet Physiol) 313A:442–451)
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