Which of the following is true for transferrin?
a. It can bind two molecules of ferrous iron.
b. It binds to a transferrin receptor found on the cell membrane.
c. It is synthesized in the kidney.
d. It is normally about 50% saturated with iron.
ANS: B
Transferrin binds to receptors on the cell membrane, which are called transferrin receptors. Transferrin has two binding sites for ferric (trivalent) iron; it does not bind ferrous iron. It is synthesized in the liver and is normally about one third saturated.
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