A nurse is discussing phentolamine (OraVerse) with a nursing student. Which statement by the student indicates the need for further teaching?
a. "Phentolamine can be used to block both epinephrine- and norepinephrine-mediated vasoconstriction."
b. "Phentolamine can be used to treat pheochromocytoma."
c. "Phentolamine is a competitive adrenergic agonist that acts selectively on alpha1 receptors."
d. "Side effects of phentolamine may include tachycardia and hypotension."
ANS: C
Phentolamine has actions on both alpha1 and alpha2 receptors; it is not selective for alpha1 receptors only. It blocks both epinephrine- and norepinephrine-mediated vasoconstriction. It is used to treat pheochromocytoma. Side effects include tachycardia and hypotension.
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