A patient taking atorvastatin (Lipitor) comes to the clinic with complaints of acute muscle pain not associated with exercise or injury. The nurse will ask questions to determine if this patient has been taking what contraindicated substance?
A) Over-the-counter (OTC) medications
B) Ginseng
C) Grapefruit juice
D) Saw palmetto
C
Feedback:
Grapefruit juice can decrease the breakdown of atorvastatin, leading to increased serum levels and toxic adverse effects, including rhabdomyolysis. Patients on this drug should be cautioned to avoid drinking grapefruit juice. OTC drugs, ginseng, and saw palmetto are not associated with increased toxicity.
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What is the drug of choice for treating malignant hyperthermia?
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Fill in the blank(s) with correct word