Outline what is required to prevent Rh D isoimmunisation in Daisy
What will be an ideal response?
Suggested response: Daisy is an O negative blood group. Rhesus isoimmunisation can only occur between a mother who has a negative blood group, and a baby who has a positive blood group. • A Kleihauer-Betke test should be performed within 2 hours of birth. The test is able to determine the number of fetal cells present in the maternal circulation. • If the baby's blood group has already been determined, and it is positive, then Daisy should receive 625 IU of Rh D-Ig as an intramuscular injection before the KleihauerBetke test result is received for prophylaxis, as she has had a ‘sensitising' event for isoimmunisation by giving birth to a positive blood group baby. • When the test results are received, Daisy may require an additional dose of Rh D-Ig; however, the dose required is dependent on the number of fetal cells detected. A standard 625 IU dose will cover a 6-mL fetal haemorrhage. • A repeat Kleihauer-Betke test should be performed 48 hours after prophylaxis in women with a fetal cell count >240 to ensure effective prophylaxis.
You might also like to view...
Sensitivity and specificity are important criteria for screening and diagnostic instruments. What is specificity?
A) Different method of measuring the same attributes yielding similar results B) Ability to differentiate the construct being measured from other similar concepts C) Instrument's ability to identify a case correctly D) Instrument's ability to identify noncases correctly.
The value of the RR is close to the value of the OR when:
a. A retrospective case-control design was used b. Absolute risk reduction is modest c. Sample size is large d. Sample size is small
The nurse is assigned to care for a client who is prescribed cholestyramine (Questran). To maintain safety for this client relative to potential effects of this drug, the nurse should monitor which laboratory test?
1. Serum glucose 2. Serum transaminases 3. Neutrophil count 4. Serum potassium level
Raven is under oral contraceptive therapy. In this case, what does breakthrough spotting most likely indicate?
A. It indicates that she is using a biphasic formulation. B. It indicates an overdose. C. It indicates that she has missed a dose. D. It indicates that she has taken oral contraceptives for more than three months.