Explain how secondary lymphoid tissues of the mucosa are (A) similar to and (B) different from secondary lymphoid tissues elsewhere in the body (the systemic immune system)
What will be an ideal response?
A. Mucosal secondary lymphoid tissues have the same general microanatomy and organization as those of secondary lymphoid tissues found at other anatomical locations, with distinct compartmentalization of B-cell and T-cell zones. Both mucosal and systemic secondary lymphoid tissues function as sites where naive lymphocytes are activated by antigen and adaptive immune responses are initiated.
B. In the systemic immune system, adaptive immune responses are activated in secondary lymphoid tissues that are quite distinct from and often distant from the site of infection. In contrast, in the mucosal immune system, the adaptive immune response is initiated at secondary lymphoid tissues at the site of infection.
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What will be an ideal response?