The nurse is caring for a patient with cancer who has been undergoing chemotherapy. The patient now suffers from oral mucositis as a result of the chemotherapy
An order is written for palifermin (Kepivance). The nurse plans to discontinue the dose at least ____ hours prior to the next chemotherapy dose.
a. 8
b. 12
c. 24
d. 72
ANS: C
The nurse should discontinue the palifermin 24 hours prior to the chemotherapy, because palifermin may increase the severity and duration of oral mucositis.
Holding the drug for 8 or 12 hours before chemotherapy is not long enough; this would increase the severity and duration of oral mucositis.
The medication need not be discontinued 72 hours before the chemotherapy. The minimum time is 24 hours in advance.
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