Explain concomitant immunity in the context of tumor immunology
What will be an ideal response
Paul Ehrlich observed that if an animal had a well-established primary tumor, then when one attempted to
establish a secondary tumor of the same cell line that the secondary tumor did not grow. The reason for this
observation is concomitant immunity, an immune reaction of the host against the tumor antigens. The immune
reaction is ineffective against an established tumor because of its bulk and intact nutrient supply, but it can
eradicate isolated tumor cells before they become established.
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