The nurse is caring for a client who has not responded to several antidepressant drugs. The nurse expects the physician to order which classification of medication for this client?

1. SNRI
2. TCA
3. SSRI
4. MAOI


Correct Answer: 4

Rationale 1: An MAOI is prescribed when other antidepressants do not work.
Rationale 2: An MAOI is prescribed when other antidepressants do not work.
Rationale 3: An MAOI is prescribed when other antidepressants do not work.
Rationale 4: An MAOI is used for treatment when other medications do not work to treat depression.

Global Rationale: An MAOI is used for treatment when other medications do not work to treat depression. SNRIs, TCAs, and SSRIs will all be prescribed prior to trying an MAOI due to the adverse reactions associate with MAOIs.

Nursing

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True False

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Explain the key difference between barbiturates and nonbarbiturates.

A. Unlike barbiturates, nonbarbiturates are CNS depressants that contain the barbituric acid ring structure in their chemical makeup. B. Unlike nonbarbiturates, barbiturates are CNS depressants that contain the barbituric acid ring structure in their chemical makeup. C. Barbiturates decrease the activity of GABA, and nonbarbiturates increase the activity of GABA. D. None of the above are correct.

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