The nurse is providing care to a client who is taking several different medications, both prescribed and over-the-counter (OTC). The nurse is consulting with the charge nurse about possible interactions. Which statement by the nurse explains the increased potential for adverse drug–drug and drug–herbal interactions?

1. "The restrictions placed by the FDA are stricter."
2. "People are using more herbs, so the risk for interaction is greater."
3. "Drugs are being developed at a faster rate than their risk can be assessed."
4. "Managed care has made a greater number of drugs available to consumers."


3

Rationale 1:"The restrictions placed by the FDA are stricter" is incorrect because FDA restrictions are broader, and cover information about non–FDA-approved uses of certain drugs.
Rationale 2:"People are using more herbs, so the risk for interaction is greater" is incorrect. While the use of herbal products has increased, this is not the underlying reason for increased adverse potential.
Rationale 3:"Drugs are being developed at a faster rate than their risk can be assessed" is correct. Because of the higher number of drugs being approved for therapy, the potential for adverse drug–drug and drug–herbal interactions is greater than ever before.
Rationale 4:"Managed care has made a greater number of drugs available to consumers" is incorrect because managed care involvement does not come into play with higher number of interactions.

Global Rationale: "Drugs are being developed at a faster rate than their risk can be assessed" is correct. Because of the higher number of drugs being approved for therapy, the potential for adverse drug–drug and drug–herbal interactions is greater than ever before. "The restrictions placed by the FDA are stricter" is incorrect because FDA restrictions are broader, and cover information about non–FDA-approved uses of certain drugs. "People are using more herbs, so the risk for interaction is greater" is incorrect. While the use of herbal products has increased, this is not the underlying reason for increased adverse potential. "Managed care has made a greater number of drugs available to consumers" is incorrect because managed care involvement does not come into play with higher number of interactions.

Nursing

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