What is the most significant difference between neostigmine and pyridostigmine?
1. Neostigmine has no adverse effects.
2. Neostigmine has a longer duration of action.
3. Neostigmine has a shorter duration of action.
4. Neostigmine cannot counteract neuromuscular blocking effect.
Correct Answer: 3
Rationale 1: Neostigmine causes a higher frequency of adverse effects.
Rationale 2: Neostigmine has a shorter duration of action than pyridostigmine.
Rationale 3: Neostigmine has a shorter duration of action than pyridostigmine.
Rationale 4: Neostigmine is indicated for the reversal of the effects of neuromuscular blocking agents after surgery.
Global Rationale: Neostigmine has a shorter duration of action than pyridostigmine. Neostigmine causes a higher frequency of adverse effects. Neostigmine has a shorter duration of action than pyridostigmine. Neostigmine is indicated for the reversal of the effects of neuromuscular blocking agents after surgery.
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