Discuss why Martina, who has blood type A, cannot receive blood type B during a transfusion
What will be an ideal response?
Martina has the antigen for A on her red blood cells. During infancy, her body built anti-B antibodies since she lacked that antigen in her blood. If she receives a transfusion of blood type B, her body will already have the anti-B antibodies in place. Agglutination will occur as the anti-B antibodies bind and clump to the foreign B antigen. The red blood cells will undergo hemolysis, hemoglobin will be released into the blood stream, and these events would lead to a transfusion reaction.
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