A patient has taken two doses of interferon Alfa-2b (Intron-A). He comes to the clinic today with the following complaints. Which symptoms would the nurse identify as common adverse effects of this therapy?
1. "I am so dizzy."
2. "I have an itchy rash on my legs."
3. "I have no appetite."
4. "I am so tired."
5. "My bones ache."
1,3,4
Rationale 1: Dizziness occurs in about half of those taking interferon.
Rationale 2: Rash is not a common adverse effect.
Rationale 3: Anorexia is a relatively common adverse effect.
Rationale 4: Fatigue occurs in about half of those taking interferon.
Rationale 5: Bone pain is not a common adverse effect.
Global Rationale: Dizziness and fatigue occur in about half of those taking interferon. Anorexia is a relatively common adverse effect. Rash and bone pain are not common adverse effects.
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