A 55-year-old male patient has been living with type 1 diabetes for many years and has begun to experience diabetic nephropathy over the past year
How will this patient's current health status influence the possible use of pseudoephedrine in the treatment of cold symptoms? A) The patient should monitor his blood glucose levels more frequently when taking pseudoephedrine.
B) The use of pseudoephedrine is absolutely contraindicated by the fact that the patient has diabetes and takes insulin.
C) The patient may require a higher-than-average dose of pseudoephedrine because of excess fluid volume secondary to renal failure.
D) The patient should use caution and will likely require a lower dose of pseudoephedrine because of his impaired renal function.
D
Feedback:
Because pseudoephedrine is excreted primarily via the kidneys, caution in patients with renal impairment is important. It may be necessary to reduce the dosage to avoid potential drug accumulation and drug toxicity. The presence of diabetes warrants caution, but it is not an absolute contraindication.
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