Which of the following peripheral nerve injuries will likely result in cellular death with little chance of regeneration?
A) Nerve fibers destroyed close to the neuronal cell body
B) Crushing injury where the nerve is traumatized but not severed
C) Cutting injury where slow-regeneration axonal branches are located
D) Incomplete amputation where tubular implants are used to fill in the gaps of nerves
Ans: A
Feedback:
The successful regeneration of a nerve fiber in the PNS depends on many factors. If a nerve fiber is destroyed relatively close to the neuronal cell body, the chances are that the nerve cell will die; if it does, it will not be replaced. If a crushing type of injury has occurred, partial or often full recovery of function occurs. Cutting-type trauma to a nerve is an entirely different matter. A number of scar-inhibiting agents have been used in an effort to reduce this hazard, but have met with only moderate success. Various types of tubular implants have been used to fill longer gaps in the endoneurial tube but again only with moderate success.
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