Which of the following changes have the potential to dramatically affect the potential difference across the plasma membrane?
A. Increased permeability of the membrane to Na+, increased intracellular concentration of K+, and any change in the rate at which the sodium-potassium pump works
B. Any change in the rate at which the sodium-potassium pump works
C. Increased permeability of the membrane to Na+
D. Increased intracellular concentration of K+
E. Increased permeability of the membrane to Na+ and increased intracellular concentration of K+
Answer: E
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