Letrozole and anastrozole are aromatase inhibitors. The mechanism of action of these drugs is to:
a. increase testosterone production in females
b. stop estrogen production in women
c. interfere with DNA replication
d. inhibit cellular growth
B
Letrozole (Femara), exemestane (Aromasin), and anastrozole (Arimidex) are aromatase inhibitors that stop estrogen production in post-menopausal women and have been approved to treat both early and advanced breast cancer.
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The client at 30 weeks' gestation with her first child is upset. She tells the prenatal clinic nurse that she is excited to become a mother, and has been thinking about what kind of parent she will be
But her mother has told her that she doesn't want to be a grandmother because she doesn't feel old enough, while her husband has said that the pregnancy doesn't feel real to him yet, and he will become excited when the baby is actually here. What is the most likely explanation for what is happening within this family? 1. Her husband will not attach with this child, and will not be a good father. 2. Her mother is rejecting the role of grandparent, and will not help out. 3. The client is not progressing through the developmental tasks of pregnancy. 4. Each family member is adjusting to the role change at his own pace.
The patient asks the nurse why generic drugs would be used and voices concerns that only the brand name product will be safe. What is the nurse's best response?
A) "Generic drugs are often less expensive." B) "Some quality control problems have been found with generic drugs." C) "Most generic drugs are very safe and can be cost effective as well." D) "Although initial cost is higher for a brand name it may cost less in the long run."
The nurse is administering a cleansing enema. Which action would indicate the need for further instruction on the process?
1. Enema solution is warmed to 40 °C (105 °F). 2. The solution container is held 12 inches above the rectum. 3. 1,000 mL of fluid is administered over 30 minutes. 4. The client is encouraged to retain the enema for 5-10 minutes.
A patient was admitted with acute abdominal and back pain. Which test results would the nurse evaluate as indicating additional testing for acute pancreatitis is likely?
1. Secretin stimulation test 2. Hematocrit level 3. Hemoglobin level 4. Serum lipase level 5. Amylase