Which of the following medications has been demonstrated to improve lung procurement after a patient has been declared brain dead?
A. pulmonary surfactant
B. third generation cephalosporin
C. dexmedetomidine
D. Solu-Medrol
ANS: D
A. Incorrect response: See explanation D.
B. Incorrect response: See explanation D.
C. Incorrect response: See explanation D.
D. Correct response: Aggressive management of brain dead patients to optimize lung procurement typically includes monitoring central venous pressure, diuresis, corticosteroids, and judicious use of fluids to maintain adequate arterial pressure, with vasopressor use as needed. An intravenous bolus of Solu-Medrol (15 ml/kg) once a patient has been declared brain dead has demonstrated to improve oxygenation and lung procurement, mainly likely by mediating the pro-inflammatory response that follows brain death
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