An adult client diagnosed with a malfunctioning hypothalamus is experiencing hormone deficiencies. Which hormones will the nurse expect to be prescribed for this client?
Standard Text: Select all that apply.
1. Thyroid hormone
2. Corticosteroids
3. Estrogen
4. Progesterone
5. Gonadotropin-releasing hormone
Correct Answer: 1,2,3,4
Rationale 1: It is more effective and less expensive to administer pituitary hormones rather than hypothalamic hormones when the hypothalamus is malfunctioning. Thyroid hormone may be prescribed for this client.
Rationale 2: It is more effective and less expensive to administer pituitary hormones rather than hypothalamic hormones when the hypothalamus is malfunctioning. Corticosteroids may be prescribed for this client.
Rationale 3: It is more effective and less expensive to administer pituitary hormones rather than hypothalamic hormones when the hypothalamus is malfunctioning. Estrogen may be prescribed for this client.
Rationale 4: It is more effective and less expensive to administer pituitary hormones rather than hypothalamic hormones when the hypothalamus is malfunctioning. Progesterone may be prescribed for this client.
Rationale 5: Initially the effect of the GnRH analogs is to increase the production of interstitial cell-stimulating hormone (in males) or follicle-stimulating hormone (in females), which increases the secretion of sex hormones. With continued therapy, however, the pituitary becomes insensitive to the effects of GnRH, and the production of sex hormones falls to near castration levels.
Global Rationale: It is more effective and less expensive to administer pituitary hormones rather than hypothalamic hormones when the hypothalamus is malfunctioning. Thyroid hormone, estrogen, corticosteroids, and progesterone may be prescribed for this client. Initially the effect of the GnRH analogs is to increase the production of interstitial cell-stimulating hormone (in males) or follicle-stimulating hormone (in females), which increases the secretion of sex hormones. With continued therapy, however, the pituitary becomes insensitive to the effects of GnRH, and the production of sex hormones falls to near castration levels.
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