Endogenous pyrogen
A. is released by infection-fighting leukocytes and has the same action as aspirin.
B. is released by the hypothalamus and acts on infection-fighting leukocytes.
C. is released by the pyloric region of the stomach and raises the temperature of digestion.
D. is released by infection-fighting leukocytes and acts on the temperature-integrating centers of the hypothalamus.
E. is released by infection-fighting leukocytes and acts on muscle tissue.
Answer: D
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