To minimize the potential for kidney damage associated with giving acyclovir intravenously, the nurse will:
1. decrease the client's protein intake two days before and two days after treatment.
2. hydrate the client intravenously during and for 2 hours after the infusion.
3. discontinue the infusion if there is any concern about a potential increase in levels of BUN.
4. limit oral fluids during infusion.
Correct Answer: 2
Rationale 1: When given IV, acyclovir is associated with nephrotoxicity, but decreasing protein intake will not decrease the potential for kidney damage.
Rationale 2: When given IV, acyclovir is associated with nephrotoxicity, so ensuring that the infusion is administered slowly and that the client is properly hydrated can lessen the potential for IV toxicity.
Rationale 3: Monitoring BUN levels is important, but another intervention is more crucial to decreasing the risk of kidney damage.
Rationale 4: When given IV, acyclovir is associated with nephrotoxicity. Oral fluids should not be limited.
Global Rationale: When given IV, acyclovir is associated with nephrotoxicity, so ensuring that the infusion is administered slowly and that the client is properly hydrated can lessen the potential for IV toxicity. Decreasing protein will have no effect. Monitoring BUN levels is important but will not prevent damage. Oral fluids should not be limited.
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